Nitrobenzene
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Just the facts
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OverviewNitrobenzene is an widely used industrial chemical used primarily to manufacture the chemical aniline (ATSDR ToxFAQs). It is a neurotoxicant and thought to be a likely Carcinogens.
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Chemical Description
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At room temperature, the chemical is a yellow viscous liquid |
Uses
The vast majority (97.5%) of nitrobenzene in use is used in the captive production of Aniline which, in turn, is used in the production of polyuerethanes. It is also used as a solvent in [petroleum] refining, producing [acetate], as a perfume for soaps, a solvent in show dyes, and in the synthesis of Acetaminophen (ATSDR Toxicological Profile).
Health Effects
Nitrobenzene is a mild irritant of the skin and eyes if they come into contact with the chemical. Chronic exposure to nitrobenzene can lead to methemoglobinemia, a condition which affects the blood's ability to carry oxygen. This condition can lead the skin to turn a bluish color and also lead to nausea, vomiting, and shortness of breath (ATSDR ToxFAQs). Liver damage may also be a byproduct of breathing in large quantities of nitrobenzene.
Nitrobenzene is now thought to be a likely Carcinogens (US Department of HHS).
External Links and References
- EPA Chemical Fact Sheet (PDF). February 1995.
- ATSDR ToxFAQs
- United States Department of Health and HUman Services. "FINAL Report on Carcinogens Background Document for NITROBENZENE" (PDF). September 19, 2002.
(ATSDR Toxicological Profile) - ATSDR Toxicological Profile for Nitrobenzene

