Corexit 9527

This oil dispersant product page contains information about the potential effects of the chemicals found in the product on human health and the marine environment. Also included is information from the EPA Product Schedule on the toxicity of this product to two aquatic organisms and its effectiveness at dispersing two types of oil

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Download the Corexit 9527 application documents submitted to the EPA

Toxicity Research

Chemical

Potential Human Health Impacts

Potential Marine Environment Impacts

Sorbitan, mono-(9Z)-9-octadecenoate
 
CAS#- 1338-43-8

• Occupational exposure has been recorded to cause contact eczema in one case (HSDB)
• Rats fed varying amounts of this compound over a span of 16 weeks experienced
liver enlargement and increased kidney weight. (EPA)
• The lowest observed adverse effect level (LOAEL) occurred when rats were eating this compound at a rate of 2.5% of their body weight. (EPA)
• In tests, rats fed this compound did not experience mortality. Observed effects included depression, decreased respiration, diarrhea for first 72 hours.(EPA)
• Reported to be practically nontoxic (HSDB)

• Aquatic vertebrates, in this particular study, rainbow trout, experienced a 0% mortality rate after a 4 day exposure to a concentration of 1000mg/liter of water. (EPA)
• Recorded biodegradation of 62% in 28 days. (HSDB)

Sorbitan, mono - (9Z) - 9 - octadecenoate, poly(oxy - 1,2 - ethanediyl) derivs.
 
CAS#- 9005-65-6

• Exposure may cause chemical pneumonitis (inflammation of lungs and difficulty breathing) and intestinal obstruction (NOAA)


• Possible eye, skin, and respiratory tract irritant (HSDB)
• Listed as practically non-toxic (HSDB)
• Occasional reports of hypersensitivity (HSDB)

ANIMAL STUDIES
• Adverse reproductive effects have occurred in experimental animals (MSDS)
• Effects on development of embryo and fetus have occurred in experimental animals (MSDS) 

...

Sorbitan, tri-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs
 
CAS#- 9005-70-3

• Slightly hazardous in case of ingestion or inhalation (MSDS)

...

Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt

CAS#- 577-11-7

• Listed as a suspected neurotoxicant (EDF)
• Toxic to blood (MSDS)                                                                                                
• Classified as moderately toxic. (HSDB) 


• Liquid is strong irritant to eye and may irritate skin by removing natural oils. (NOAA)
• Ingestion causes diarrhea and intestinal bloating. (NOAA)


ANIMAL STUDIES                                                                                                           
• Oral exposure caused these effects in rats: low body weight (of adults), decreases
in maternal weight gain, low birth weight of pups, and malformed fetuses.
• Severely damaging to rabbit eyes at 10% concentration. (HSDB)
• Mice and rats repeatedly exposed to butanedioic acid showed gastrointestinal problems, reduced weight gain, and death at certain doses. Dogs did not experience any adverse effects from repeated exposure. (toxipedia)
•Exposure to the skin has caused these effects in rabbits: erythema, edema, premature skin death, irritation, and coarse skin. (toxipedia)
• High doses from oral exposure have caused these effects in mice and rats: depression, diarrhea, lethargy, irritation and hemorrhage of the gastrointestinal tract, and death. (toxipedia)

• Possibility of absorbing to sediment (HSDB)
• Slight acute toxicity to fish (PANNA)

ANIMAL STUDIES
• In tests, fish experienced a 50% or higher mortality rate when concentrations of butanedioic acid, 2-sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt were between 28-37mg/liter of water after 4 complete days of exposure. (EPA)
• In tests, 50% or more aquatic invertebrates experienced negative effects from a 2-day exposure to a concentration of 36.2mg/liter of water. (EPA)
• Slightly toxic to bluegill sunfish (EPA)
• In tests, rainbow trout died at levels of 40-80mg/L (EPA)
• In tests, rainbow trout died within 1 hour of exposure to 50-100 ppm (EPA)

2 - Propanol, 1 -(2 - butoxy - 1 - methylethoxy) -
 
CAS#- 29911-28-2

• Listed it as a suspected neurotoxicant. (EDF)


• Prolonged exposure to skin may cause drying of the skin, leading to dermatitis (MSDS)
• Slightly irritating to eyes

ANIMAL STUDIES
• In tests, fish experienced a 50% mortality rate in concentrations of
841 mg/liter of water for 4 days (IUCLID)
• Aquatic invertebrates did not experience any effects after exposure to a concentration of 1000mg/liter of water for 2 days (IUCLID)

Distillates (petroleum), hydrotreated light
 
CAS#- 64742-47-8

• Confirmed animal carcinogen with unknown relevance to humans (MSDS1)                            
• Prolonged inhalation of high cooncentrations may damage respiratory system (MSDS2)


• Frequent and prolonged skin contact may cause dermatitis (MSDS2)
• Exposure by inhalation can cause dizziness, headache, nausea, drowsiness, and unconsciousness (NIOSH)
• Exposure to the skin can cause dryness. (NIOSH)
• Exposure to the eyes can cause redness (NIOSH)


ANIMAL STUDIES                                                                                                                                       
• After oral ingestion, rats: lost weight and hair (p. 3), exhibited high platelet counts (p. 4), changes in serum chemistry (p. 4); increased kidney, liver, adrenal and testes size and chemistry (pp. 4-5 (EPA HS)

• Listed as harmful to aquatic organisms (NIOSH)
• Moderate acute toxicity to fish (PANNA)

Ethanol, 2-butoxy-

CAS#- 111-76-2

• Listed as a possible carcinogen (HSDB)
• While 2-Butoxyethanol is not registered as a carcinogen, the New Jersey Department of Health Hazardous Substance Fact Sheet states it "should be handled as a CARCINOGEN--WITH EXTREME CAUTION." The same fact sheet reports that it has been shown to cause liver cancer in animals. (NJ Fsheet)
• Prolonged or repeated exposures can cause damage to the liver and kidneys (NJ Fsheet)
• Exposure may damage developing fetus (NJ Fsheet)
• People exposed to high levels of 2-butoxyethanol for several hours reported irritation of the nose and eyes, headache, a metallic taste in their mouths, and vomiting (ASTDR)



• Irritant to eyes, nose, and throat (HSDB)
• The Occupational Safety and Health Administration has set an exposure limit of 50 parts of 2-butoxyethanol per million parts of air (50 ppm) for an 8-hour workday, 40-hour workweek. (ASTDR)
• If large amounts are consumed orally it can cause breathing problems, low blood pressure, blood in urine, lowered levels of hemoglobin, and high levels of acid in the body. Coma, following consumption of large amounts, has been recorded in some cases (ASTDR)


ANIMAL STUDIES
• Limited evidence that it may damage male reproductive system and affect female fertility in animals (NJ Fsheet)
• Low red blood cell counts in the spleen, kidney, and liver have been recorded in a number of studies on animals such as dogs, monkeys, and mice (ASTDR)

• Potential to biodegrade rapidly in water (HSDB)
• Not expected to absorb to suspended solids or
sediment (HSDB)
• Listed as not acutely toxic to crustaceans, fish, and zooplankton (PANNA)

 Toxicity Studies

Test Mixture

96 hr. LC50 M. beryllina (estuary fish)

48 hour LC50 M. bahia (shrimp)

COREXIT 9527

14.57 ppm

24.14 ppm

No. 2 Fuel Oil

10.72 ppm

16.12 ppm

COREXIT 9527 and No. 2 Fuel Oil

4.49 ppm

6.60 ppm

LC50= Lethal concentration of a chemical or mixture that kills 50% of a sample population
ppm= Parts per million

Effectiveness of Product at Dispersing Oil

Type of Oil

Efficacy

Prudhoe Bay Crude

37.40%

S. Louisiana Crude

63.40%

References


Toxicity Research

Sorbitan, mono-(9Z)-9-octadecenoate

HSDB- http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f?./temp/~BRccvA:1
EPA- http://iaspub.epa.gov/oppthpv/quicksearch.display?pChem=101126"

Sorbitan, mono-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs.

NOAA- http://cameochemicals.noaa.gov/chemical/20939
HSDB- http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f?./temp/~QeobaP:1
MSDS- http://fscimage.fishersci.com/msds/40200.htm

Sorbitan, tri-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs.

MSDS- http://www.sciencelab.com/msds.php?msdsId=9926646

Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt

NOAA- http://cameochemicals.noaa.gov/chemical/8582
EDF- http://scorecard.goodguide.com/chemical-profiles/summary.tcl?edf_substance_id=577-11-7
EPA- http://iaspub.epa.gov/oppthpv/Public_Search.PublicTabs?SECTION=1&epcount=3&v_rs_list=25094016,25093427,25093439
MSDS- http://www.sciencelab.com/msds.php?msdsId=9923877
PANNA- http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC33310

2-Propanol, 1-(2-butoxy-1-methylethoxy)-

IUCLID- http://ecb.jrc.ec.europa.eu/iuclid-datasheet/29911282.pdf
EDF- http://scorecard.goodguide.com/chemical-profiles/summary.tcl?edf_substance_id=29911-28-2
MSDS- http://megaloid.ca/MSDS/Glycol%20Ether%20DPnB.pdf

Distillates (petroleum), hydrotreated light

NIOSH- http://www.cdc.gov/niosh/ipcsneng/neng1379.html
PANNA- http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC33064
MSDS1- http://fscimage.fishersci.com/msds/89683.htm
MSDS2- http://www.chemcas.com/msds_archive/part2/cas/gm_msds/metprep_co_uk---oillub.asp

Ethanol, 2-butoxy-

HSDB- http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f?./temp/~gtigpw:1
ASTDR- http://www.atsdr.cdc.gov/toxfaqs/tfacts118.pdf
PANNA- http://www.pesticideinfo.org/List_AquireAcuteSum.jsp?Rec_Id=PC35051

Toxicity Studies and Effectiveness at Dispersing Oil

COREXIT 9527 Product Schedule

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